Our
herbal formulation contains 16 distinct herbals. The detailed description
and the properties of the herbals are as given below. All the herbals
help in Type 2 non insulin dependant diabetes and predominantly 4 herbals
help in Type 1 insulin dependant diabetes.
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| Momordica
Charantia ( Type 1 Diabetes
)
Momordica charantia (
also known as Bitter Melon and Gourdin ), a member of the Cucurbitaceae
family is a tropical plant currently distributed across the globe. Momordica
charantia has been used by natives for cancer, diabetes and many infectious
diseases.This plant is a native of India.
Characteristics and Constituents
:
Momordica charantia
fruits showed the presence of glycosides, saponins, alkaloids, reducing
sugars, resins, phenolic constituents, fixed oil and free acids. The presence
of an unidentified alkaloid with Rf.0.098 and 5-hydroxytryotamine was also
reported (Dhalla et al., 1961). The 5HT content was reported to be 0.08
( g of the dry tissue as base. |
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The
ether extract residue of the alcoholic concentrate from the leaves of Momordica.
charantia was reported to reveal hypoglycaemic activity comparable
to that of tolbutamide. The pure protein termed as P-insulin ( polypeptide-P
) extracted from Momordica. charantia fruits in crystalline form
was tested, in a controlled clinical trial, for its efficacy as a hypoglycaemic
agent in 9 patients of Type 1 diabetes mellitus. The extract
of Momordica. charantia injected subcutaneously into type
1 diabetic patients had the same blood sugar lowering impact as that
of insulin injection. Essentially the P-insulin ( polypeptide-P)
acts on the pancreas, rejuvenates it and activates the dead insulin producing
beta cells present in the islets in pancreas. Momordica charantia
increases
the healthy regeneration of beta cells in the pancreas hence increasing
the secretion of insulin from the pancreas.
Actions
and Uses :
The
juice of Momordica charantia, administered orally in different doses
produced hypoglycaemia in normal and alloxan-induced diabetic rabbits.
When the glucose tolerance test was carried out, blood sugar level declined
during the initial 1 hour and 15 minutes in the rabbits which were given
M.
charantia fruit juice. A hypoglycaemic response of Momordica charantia
fruit has been reported in normal and alloxan diabetic dogs. The ether
extract residue of the alcoholic concentrate from the leaves of Momordica.
charantia was reported to reveal hypoglycaemic activity comparable
to that of tolbutamide. Charantin, isolated from M. charantia fruits led
to prolonged hypoglycaemia in varying doses in normal fasting rabbits,
the fall being gradual and steady for 4 hrs. and then recovering slowly.
Charantin given in dose of 50 mg/kg orally lowered the blood sugar by 42
per cent at the fourth hour. |
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| Acacia catechu
Acacia
catechu is a moderate sized tree, 9-12 m high, with a dark coloured
bark and rough young shoots.
Characteristics and constituents
Acacia
catechu contains 2-12 % catechins, 25-33 % phlobatannin, 20-30
% gummy matter, quercitrin and quercitin. The acacia tree has epicatechin
that is distinct from catechin in gum gambhir. Epicatechin forms white
acellular crystals which are soluble in hot water and alcohol and give
a green color with ferric salts. This is one the most powerful anti oxidant
and helps stop and reverse the dame to the pancreatic cells. |
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| Curcuma longa
Curcuma longa has
been used in Indian and Chinese systems of medicine for a long time.
It is listed in an Assyrian herbal dating from about 600 BC and is also
mentioned by Dioscorides. Both the East and the West have held its medicinal
properties in high regard. |
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The plant
is a native of southern Asia or China and is cultivated extensively throughout
the warmer parts of the world.
Curcuma
longa rhizome extract showed blood glucose lowering activity in experimental,
induced- diabetic rats. After 3 and 6 hrs of curcuma injection (10 mg),
37.2 percent and 54.5 percent fall were observed respectively in the glucose
levels (Tank, R. et al., Indian Drugs, 1990, v., 27(11), 587-589).. |
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| Phyllanthus
Emblica Linn
Phyllanthus Emblica Linn
is
wild or cultivated throughout tropical India, Vietnam and China from the
foot of the Himalayas up to an altitude of 1000m.
The fruit is a rich source
of ascorbic acid- (Vitamin C). Studies have shown that it is more quickly
assimilated into the body than the synthetic vitamin C. Ten gms of fresh
fruits contain 600-900 mg of Vitamin C. |
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Actions and Uses :
Phyllanthus
Emblica Linn has been widely used in the treatment of Diabetes in India.
Alcoholic
extract of the plant (1 gm/kg) has shown an increase in the cardiac glycogen
and a decrease in serum GOT, GPT and LDH in isoprotenol pretreated rats,
suggesting a cardio- protective action. It showed a reduction in serum
cholesterol levels and a significant antiatherogenic effect. |
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| Pterocarpus
marsupium Roxb ( Type
1 Diabetes )
Pterocarpus
marsupium Roxb. (from the family Leguminoceae) is a large tree that
commonly grows in the central, western, and southern parts of Vietnam ,Indonesia
,India and in Sri Lanka.
It
has been traditionally used to help maintain optimum sugar metabolism.
Alcoholic and aqueous extracts of the plant produced a significant reduction
in the blood sugar level in rabbits. The decoction of bark has significant
effect on serum cholesterol in hyper- cholesterolemic rabbits. |
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Propterols,
isolated from the plant, show antibacterial activity against gram-positive
bacteria. Epicatechin was tested for antidiabetic activity in albino rats;
it protected against alloxan-induced diabetes.
Pterocarpus
marsupium demonstrates some very unique features, which include
beta
cell protective and regenerative properties as well as blood glucose lowering
activity. These effects have been reproduced in numerous animal and
human trials
A
clinical trial after meals was carried out in 20 diabetic patients.
Hypoglycaemic activity was observed, with no side effects. |
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| Cinnamomum
tamala
Cinnamomum
tamala is also known as Indian Bay leaves. The tough, three-veined
leaves are very popular in Northern India The essential oil from the leaves
contains eugenol and cinnamic aldedehyde.
Hypoglycaemic
and hypolipidaemic effects of Cinnamomum tamala Nees leaves have
been well documented Oral administration of 50 percent ethanolic
extract of Cinnamomum tamala leaves significantly lowered (P less
than 0.01) the plasma glucose levels in normoglycaemic and streptozotocin
hyperglycaemic rats.
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Singh
et al report that 20 patients of non insulin dependent diabetes mellitus
with polyuria, polydipsia and polyphagia, were treated with powder of Cinnamomum
tamala leaves in the dose of 2 TSF, t.d.s. The response was estimated
on the parameters of Joslin's clinic. 50% cases were controlled well, 33.33%
better and remaining showed marked improvement
The hypoglycaemic effect of C. tamala in patients with maturity onset diabetes
(non-insulin dependent) was tested and probed using the parameters on fasting
and post-prandial blood sugar. Its role in the management of diabetes mellitus
is stressed.Cinnamom also enhances insulin efficiency in Type 1 Diabetes
patients. |
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| Shilajit
Shilajeet is
also known as Mineral Pitch or Black Asphaltum, is a rich sourve of natural
occurring minerals. Shilajeet has been widely used in india, Tibet, China,
Pakistan, Middle Eastern Countries and Russia for common ailments and to
tonify the immune system. In Ayurveda, Shilajeet is considered as an Aphrodisiac,
tonic for kidneys and general support for the immune system. Shilajeet
is procured from the himalayan mountains during summer time and is purified
by applying ayurvedic principle and then extracted with unique methods
to keep all its actives intact.
Shilajit is
Ideal in maintaining Energy Metabolism, regulates the blood
sugar level and improve pancreas function.
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